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pentobarbital will lower the extent or result of celecoxib by impacting hepatic enzyme CYP2C9/ten metabolism. Minor/Significance Unknown.pentobarbital will enhance the degree or outcome of ivosidenib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of ivosidenib with potent CYP3A4 inducers re